Leishmania Western Blot IgG (12T)
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Leishmania Western Blot IgG (12T) (LES-WB12G) is a single use qualitative test of serological IgG diagnosis by Immunoblot Assay of leishmaniasis intended for confirmatory testing of a positive or equivocal result obtained through classic screening tests. Kit of 12 tests.
LEISHMANIA Western Blot IgG TEST
The French Haute Autorité de Santé (HAS) recommends the immunoblot for the diagnosis of VL and cutaneous/mucosal leishmaniases as a confirmation of the screening techniques (Argumentaire HAS, 2017).
For patients coinfected with HIV, even though DNA detection by amplification techniques are more sensitive, detection of low titers of antibodies is highly helpful for the diagnosis (Cota et al., 2012).
Thanks to its performances, the Western Blot technique can be useful as an epidemiological marker of the disease and allows a precocious diagnosis, especially with poorly evocative symptoms (Biglino et al., 2010, Pomares et al., 2012, Saghrouni et al., 2012).
In order to meet this demand, LDBIO Diagnostics developed a reliable test based on the Western blot technique. Associated with highly sensitive natural antigens, the LEISHMANIA Western Blot IgG test is a robust confirmation technique of classical screening tests.
The LEISHMANIA Western Blot IgG test allows the differentiation of the 14 and 16 kDa antigens, which are specific of Leishmania (Mary et al., 1992). Specificity and remarkably high sensitivity of the immunoblot technique can greatly improve the screening of visceral leishmaniasis.
Each kit is composed of sensitized and precut strips, the ready-to-use liquid reagents, and the positive control serum.
