Nipah Virus Glycoprotein G Recombinant Protein (Human Fc) (100µg) (Special Terms Apply*)
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Nipah Virus Glycoprotein G Recombinant Protein (Human Fc) (100µg) (Special Terms Apply*) (QTXAG-492-100) is recombinant Nipah virus glycoprotein G, comprising amino acids 71-602 and incorporating a human IgG1 Fc tag, expressed in mammalian HEK293 cells. Greater than 90% purity.
Nipah virus glycoprotein G has a globular head domain formed of a six-bladed beta sheet-propeller, connected via a flexible stalk domain to a transmembrane anchor. The G protein binds to the cellular receptors ephrin B2 and ephrin B3, mediating viral attachment. Following attachment Nipah Virus glycoprotein G undergoes a conformational change that leads to triggering of glycoprotein F which leads to membrane fusion.
Nipah virus glycoprotein G is a recombinant protein expressed in mammalian HEK293 cells. It is presented as a fusion protein with a human Fc tag linked to the C-terminus of glycoprotein G, amino acids 71-602. This protein migrates at approximately 110kD in reducing SDS-PAGE analysis.
*Special Terms: Please see product specification details below and our Ordering page for details.
Q-TOX Term 2: Minimum Order Volume of 1000µg on Orders Requiring Dry Ice Shipment
