Aspergillus Western Blot IgG (24T)
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Aspergillus Western Blot IgG (24T) (ASP-WB24G) is a single use qualitative test of serological IgG diagnosis by Immunoblot Assay of aspergillosis intended for confirmatory testing of a positive or equivocal result obtained through classic screening tests. Kit of 24 tests.
Aspergillosis are infections due to ubiquitous fungi of the Aspergillus genus. Various pathologies induced depend on several intrinsic characteristics of the fungus itself and on its host, which will condition the virulence of the disease.
Amongst hundreds of Aspergillus species, more than 20 are currently reported to be pathogneous for humans, but new pathogenous species are regularly identified (Gauthier et al., 2016). However, Aspergillus fumigatus is the most commonly encountered species of the genus. It is estimated to be responsible of more than 80% of human pathological manifestations, but this proportion varies depending on clinical forms and geographical location.
A. fumigatus is an opportunistic saprophytic pathogen, naturally present in all kind of environment (soils, air, aquatic habitats, on plants…). Extremely resistant, fungal conidiae penetrates the host mostly by inhalation, but also by ingestion or cutaneous contact through wounds. As they are extremely thin, Aspergillus conidia can reach pulmonary alveolus. After their endocytosis by epithelial cells of the host, they germinate and colonize by dissemination of hyphae, that can reach bloodstream and thus invade other organs (Paulussen et al., 2017).
