Crimean-Congo Haemorrhagic Fever virus (CCHFV) glycoprotein C (Gc), sheep Fc-tag (100µg) (Special Terms Apply*)
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Crimean-Congo Haemorrhagic Fever virus (CCHFV) glycoprotein C (Gc), sheep Fc-tag (100µg) (Special Terms Apply*) (QTXAG-578-100) is recombinant CCHFV major glycoprotein Gc produced in HEK293 cells and purified from culture supernatant. The C-terminal transmembrane domain and the intravirion tail of the protein have been replaced by a 15 amino acid glycine-serine linker and the sheep IgG Fc region.
CCHF virus Gc with sheep Fc-tag (Gc, previously referred to as G1), to meet the increasing need for high quality reagents for research into diagnosis of CCHF, as well as vaccine development. We also produce a human Fc-tag version of this CCHF virus Gc protein.
During Crimean Congo Hemarrhagic Fever virus (CCHFV) infection the virus encodes a polyprotein which undergoes a complex proteolytic cascade to generate a number of precursor proteins in addition to two mature structural glycoproteins, Gn and Gc. The mature Gn (37-kDa) and Gc (75-kDa) proteins form the predominant structural glycoprotein components of the virus.
*Special Terms: Please see product specification details below and our Ordering page for details.
Q-TOX Term 2: Minimum Order Volume of 1000µg on Orders Requiring Dry Ice Shipment
