Human IgG1 Anti Dengue Virus NS1 Serotype 1 Antibody (OB4) (100µg)

Human IgG1 anti Dengue virus NS1 antibody is specific for the NS1 protein of Dengue virus serotype 1. It demonstrates negligible cross-reactivity with NS1 proteins from other Dengue virus serotypes or with other flaviviruses. No cross-reactivity is seen with Chikungunya virus proteins (E1, E2 and C).

This human IgG1 anti Dengue virus serotype 1 NS1 monoclonal antibody has been prepared by chimerization from the mouse monoclonal antibody (clone OB4). The original variable domains of this antibody have been retained, whilst the constant regions have been replaced with human IgG1.

The antibody is designed to provide a control for assays in which human serum is tested for antibodies specific for Dengue serotype 1 NS1 protein, which will result from the immune response following an infection with Dengue virus. The antibody has been tested in ELISA using recombinant Dengue virus serotype 1 NS1 protein as the target antigen.