Oropouche Virus Gc Protein, Mouse Fc (500µg) (Special Terms Apply*)
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Oropouche Virus Gc Protein, Mouse Fc (500µg) (Special Terms Apply*) (QTXAG-466-500) is recombinant oropouche virus major glycoprotein Gc, comprising amino-acids 517-1373 from the M segment polyprotein and incorporating a mouse IgG1 Fc tag, expressed in mammalian HEK293 cells. Purity greater than 60%.
A range of Oropouche virus antigens to facilitate research into the virus, and to support immunoassay develpment. Oropouche virus Gc protein is a type I integral transmembrane protein, which is further modified by N-linked glycosylation. Together with Gn protein it forms spikes on the virus particle and is essential for viral attachment and cell fusion. It has been described that for certain bunyaviruses, Gn and Gc are targeted by neutralizing antibodies Oropouche virus Gc protein was expressed in mammalian HEK293 cells. The transmembrane region of the protein has been replaced with mouse IgG Fc, via a glycine-serine linker. The purified protein is approximately 140kD on analysis by reducing SDS-PAGE.
*Special Terms: Please see product specification details below and our Ordering page for details.
Q-TOX Term 2: Minimum Order Volume of 1000µg on Orders Requiring Dry Ice Shipment
